ISMIOS™

An AI based, purpose-built solution for cancer second opinion services and long-term surveillance

Discover possibilities with ISMIOS™

Access expert second opinions, personalized recommendations, and secure care coordination—all in one platform. ISMIOS™ connects patients, physicians, and diagnostic systems to simplify collaboration and improve outcomes.

PACS & DICOM Integration

Connect directly with hospital systems and diagnostic facilities for seamless collaboration.

Customizable Report

Easily create and share reports tailored to each patient’s needs and workflow.

HIPAA-Compliant Uploads

Securely upload and store diagnostic images and reports with end-to-end encryption.

Trusted Telehealth R

Access verified provider profiles and patient reviews directly within ISMIOS.

Streamlined Second Opinions

View, download, and share second opinion reports in one secure hub.

AI-Powered Insights

Leverage intelligent analysis to support clinical decisions and long-term monitoring

Manage your cancer second opinion records effortlessly

Get secure, virtual access to your medical records from anywhere. Our platform simplifies every step — from signing up and uploading files to connecting with world-class physicians for expert second opinions and video consultations. Designed for global collaboration, it supports physician panels across multiple regions to deliver faster, more accurate care.

We put patients first

Register for services

Patients and physicians can easily register for cancer second-opinion services with a single click. Reports are reviewed within 72 hours, and video consultations are scheduled within three days—at your preferred time.

Patient services

Securely upload diagnostic images and reports through our HIPAA-compliant platform. We automatically collect records from your hospitals and clinics, and you can book online consultations or manage ongoing care through MyOncCompanion™.

Physician services

Request second opinions or treatment reviews for your patients, validate care plans, and stay connected through MyOncCompanion™. Trusted Telehealth® helps you ensure every follow-up is on track and every patient receives continuous, coordinated care.

Frequently Asked Questions About Getting
A Second Opinion for Cancer Treatment

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The answer is ‘Yes”. Cancer patients should explore the treatment options and validate an initial diagnosis. Between 10 and 60% of second opinions result in a diagnosis, management, or prognosis change.

Payne VL, Singh H, Meyer AN, Levy L, Harrison D, Graber ML. Patient-initiated second opinions: systematic review of characteristics and impact on diagnosis, treatment, and satisfaction. In: Mayo Clinic Proceedings. Amsterdam: Elsevier; 2014.

As seeing a specialist in a specialized center is always a good idea, you usually don’t have to. Trusted Telehealth® works with many physicians employed at the nation’s foremost cancer centers, all US board certified and uniquely qualified to treat or render an opinion about the condition for which you seek a second opinion. Most of the time, we can spare you costly travel, unnecessary co-pays, and, most importantly, TIME.

You can cancel your selected service at any time if the service has not already been completed. If you choose long-term management for your case, you will have the opportunity to opt-out.

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Yes. You can ask questions through your portal, and one of our staff members will respond as soon as possible. You can book an appointment to speak with one of our physicians. In the event of an emergency, please see the nearest emergency room.

Contact us by email – info@tth.ai – or book an appointment with one of our staff members. If you are an established patient with a valid account, you can book an appointment with one of our physicians through the portal.

To ensure the security and safety of our platform, we want to verify that every visitor to our platform is a natural person.

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